Micro/nanomotors, based on a multiples propulsion mechanisms, have been developed over the past decade toward diverse applications. The ability of the micro/nanomotors to rapidly move in different mediums represents a novel approach in areas like environmental remediation, diseases treatment, self-healing and biosensors. In this presentation, we journey from the production and use of chemically powered to externally actuated (fuel-free) micro/nanovehicles platforms and its prospects and challenges for such practical propelling systems.