Abstract – Publication

Flexible, bifunctional sensing platform made with biodegradable mats for detecting glucose in urine.
GOMES, Nathalia Oezau; PASCHOALIN, Rafaella Takehara; BILATTO, Stanley; SORIGOTTI, Amanda Rinaldi; FARINAS, Cristiane Sanchez; MATTOSO, Luiz Henrique Capparelli; MACHADO, Sergio Antonio Spinola; OLIVEIRA JUNIOR, Osvaldo Novais de; PEREIRA, Paulo Augusto Raymundo.
Abstract: We report on a flexible, bifunctional platform made with solution-blow spinning fiber mats of polylactic acid (PLA) and polyethylene glycol (PEG). The PLA/PEG mats were designated bifunctional because they were used as a substrate for screen-printed carbon electrodes (SPCEs) and as a matrix to attach glucose oxidase (GOx) covalently. By attaching GOx only on the fiber mats, and not on the SPCE, the detection of hydrogen peroxide generated from glucose oxidation by the enzyme was efficient, especially with Prussian blue (PB) nanoparticles electrodeposited on the SPCE surface. The bifunctional device detected hydrogen peroxide (H2O2) in synthetic and human urine at a low applied potential (0 V vs Ag/AgCl) in the range from 1.0 to 6.0 mM, with a detection limit of 0.197 mM, being also interference-free. The biosensor whose cost is
ACS Sustainable Chemistry & Engineering
v. 11, n. 6, p. 2209-2218 + supporting information: S1-S16 - Ano: 2023
Fator de Impacto: 9,224
    @article={003119893,author = {GOMES, Nathalia Oezau; PASCHOALIN, Rafaella Takehara; BILATTO, Stanley; SORIGOTTI, Amanda Rinaldi; FARINAS, Cristiane Sanchez; MATTOSO, Luiz Henrique Capparelli; MACHADO, Sergio Antonio Spinola; OLIVEIRA JUNIOR, Osvaldo Novais de; PEREIRA, Paulo Augusto Raymundo.},title={Flexible, bifunctional sensing platform made with biodegradable mats for detecting glucose in urine},journal={ACS Sustainable Chemistry & Engineering},note={v. 11, n. 6, p. 2209-2218 + supporting information: S1-S16},year={2023}}

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