Follow-up of pressure ulcer treatment with photodynamic therapy, low level laser therapy and cellulose membrane.
ROSA, Luciano Pereira; SILVA, Francine Cristina da; LUZ, Suzete Carvalho Landulfo; VIEIRA, Regiane Lima; TANAJURA, Beatriz Rocha; GUSMÃO, Alana Gonçalves da Silva; OLIVEIRA, Janeide Muritiba de; NASCIMENTO, Fabiana de Jesus; SANTOS, Nathalia Aparecida Campanário dos; INADA, Natalia Mayumi; BLANCO, Kate Cristina; CARBINATTO, Fernanda Mansano; BAGNATO, Vanderlei Salvador.
ROSA, Luciano Pereira; SILVA, Francine Cristina da; LUZ, Suzete Carvalho Landulfo; VIEIRA, Regiane Lima; TANAJURA, Beatriz Rocha; GUSMÃO, Alana Gonçalves da Silva; OLIVEIRA, Janeide Muritiba de; NASCIMENTO, Fabiana de Jesus; SANTOS, Nathalia Aparecida Campanário dos; INADA, Natalia Mayumi; BLANCO, Kate Cristina; CARBINATTO, Fernanda Mansano; BAGNATO, Vanderlei Salvador.
Abstract: Objective: A pressure ulcer (PU) is an area of tissue trauma caused by continuous and prolonged pressure, often associated with hospitalised patients immobilised due to neurological problems, negatively affecting their quality of life, and burdening the public budget. The aim of this study was to report the follow-up, for 45 weeks, of three patients with neurological lesions due to trauma who subsequently developed PUs, and who were treated with a combination of photodynamic therapy (PDT), low level laser therapy (LLLT) and cellulose membrane (CM). Method: PDT was mediated by the photosensitiser curcumin on a 1.5% emulsion base. Blue LED light at 450 nm was delivered continuously for 12 minutes at an irradiance of 30mW/cm2 and total energy delivered to the tissue was 22J/cm2. LLLT was performed with 660 nm laser, punctuated and continuous, twice a week with parameters: spot size 0.04cm2, power of 40mW, 10 seconds per point, fluence of 10J/cm2 and irradiance of 1000mW/cm2. Results: All PUs had a significant reduction (range: 95.2-100%) of their area after 45 weeks of follow-up and two PUs had complete healing at 20 weeks and 30 weeks. All of the PUs showed a reduction in contamination with the PDT treatments in different proportions. Conclusion: From the results obtained, we conclude that the combination of PDT, LLLT and CM is a promising treatment for PU healing.
@article={003029517,author = {ROSA, Luciano Pereira; SILVA, Francine Cristina da; LUZ, Suzete Carvalho Landulfo; VIEIRA, Regiane Lima; TANAJURA, Beatriz Rocha; GUSMÃO, Alana Gonçalves da Silva; OLIVEIRA, Janeide Muritiba de; NASCIMENTO, Fabiana de Jesus; SANTOS, Nathalia Aparecida Campanário dos; INADA, Natalia Mayumi; BLANCO, Kate Cristina; CARBINATTO, Fernanda Mansano; BAGNATO, Vanderlei Salvador.},title={Follow-up of pressure ulcer treatment with photodynamic therapy, low level laser therapy and cellulose membrane},journal={Journal of Wound Care},note={v. 30, n. 4, p. 304-310},year={2021}}